Defendants involved the Land and Housing Bureaus at the municipal and district levels as well as the Municipal Government; in the subsequent appeal process defendants also involved courts of preliminary trials and secondary trials (based on field interviews on Nov. 11, 2005 and Nov. 24, 2005).
The registry listed a primary outcome measure for all trials and secondary outcome measures for 18 trials.
The results of included clinical trials and secondary data analyses are reviewed with a focus on clinical efficacy, safety, and tolerability of vilazodone in the treatment of major depression.
We collected the following information: name of the active substance, year of approval, indication, design of the pivotal trials, number of patients in each trial, primary and secondary end points supporting the approval and difference in survival between arms, when available.
Cost-effectiveness analysis will assess the trial primary and secondary outcomes based on the duration of the trial itself first and then an extension of projected outcomes beyond the observed trial follow-up, so these analyses will examine the direct and indirect costs and the reduction in pain, improvement in physical or psychosocial function.
This is an important study, since it explores the patients' viewpoint rather than usual clinical trial primary and secondary end point such as reduction in headache days or efficacy of acute medication at 2 h.
Changes from baseline in mean monthly EA-ID and PI-ID over the final 3 months (months 4 6) of the double-blind treatment phase (DBTP) were assessed as pre-specified exploratory endpoints in the STRIVE trial; primary and secondary endpoints are reported separately.
To probe the distribution of attention, colors were presented on different segments of the curves at various intervals during a trial, and the secondary task was to report one of these colors.
However, practical concerns must be addressed if the efforts of clinical trial funders, journals, and secondary users of clinical trial data to promote data sharing are to succeed.
With these strategies in mind, we used a combination of a trial-and-error approach and secondary structure designs computed by RNA Designer [ 40] to obtain mutant sequence with desired structural characteristics.
