(ii) Information about clinical trials and knowledge, clinical professionals, and trail investigators can be well constructed and maintained as a knowledge base for improving quality and efficiency of future clinical trials.
These same risk factors can also be used to select at-risk individuals for clinical trials, and knowledge of correlates of circulating 25(OH D also aids in the analysis and interpretation of observational study results.
The epidemiology of DSPS is still in its infancy, and while the present study contributes to an understanding of the prevalence and correlates of the symptoms, more studies are needed to bridge the gap between our knowledge based on well-characterized DSPS in clinical trials, and knowledge from epidemiological studies.
According to new trials and knowledge of myocardial remodelling as a crucial factor in HF development, slowing or reversing the progression of the disease is recognized as important goal of novel therapy (e.g., inhibition of angiotenzin-renin-aldosteron system) [ 36].
While this could relate to the numerous blood samples taken in the trial ward and knowledge about the trial's pharmacokinetic objectives, it persisted in their descriptions of follow-up visits, when tests were far fewer.
To date, there is no adequately powered randomized clinical trial available, and knowledge is based on observational trials or trials before the era of primary PCI.
The Bush administration denied Rasul access to counsel, the right to a trial, and any knowledge of the charges against him.
Most of us have never even been in a courtroom, let alone a murder trial, and our knowledge of the legal system doesn't encompass much more than a few episodes of Law and Order or The Good Wife.
Patients without MRSA were not permitted to complete the clinical trial, and investigator knowledge of certain specific gram-negative risk factors (gram stain results, colonization history, or local ecology) would likely discourage enrollment of patients with gram-negative infections.
However, to date, high quality clinical trials and thorough knowledge of the physiologic mechanisms involved is lacking.
