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Criteria: primary end point of the trial achieves statistical significance.
Within a given trial, choices related to study design have a major impact on whether a trial achieves successful enrollment.
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Some volunteers in the US Phase 1 clinical trial achieved AMA1 antibody levels that partially blocked P. falciparum invasion of erythrocytes; however, the majority of volunteers displayed low antibody levels with little or no in vitro inhibition of parasite invasion [16].
Our trial achieved response and disease control rates of 55.6 and 91.7 %, respectively.
Our trial achieved results at least comparable with the more targeted interventions based in general practice.
Hence the NNIPPS trial achieved the power necessary to detect the hypothesized drug effect.
4 5 This suggests that the sampling method used in the trial achieved a representative sample.
In contrast Hanlon's trial achieved a change of five points [ 15].
89 In CLL, a separate phase II trial achieved a partial response of 18%.
Interestingly, fifteen patients on the trial achieved cumulative anthracycline doses of 300 mg/m (two with previous exposure).
62 Even a randomized trial achieved participation rates of just over 60% for attendance at exercise sessions.
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