Suggestions(1)
Exact(12)
The only large trial accrued 509 patients diagnosed with papillary or follicular thyroid cancer in Northern India [10].
The clinical trial accrued a total of 47 patients.
This trial accrued 26 patients with lymphoma or MM.
This was not an unexpected finding as this trial accrued patients when levamisole's efficacy was beginning to be challenged.
The E1690 trial accrued patients from 1991 until 1995, was unblinded in 1998, and published in 2000 [ 9].
Unfortunately, interpretation of the results is hindered since the trial accrued slowly and was closed after 85 of a planned 120 patients had been randomized.
Similar(48)
Our results are also comparable to those obtained in a large confirmatory trial accruing more than 1000 patients (Wilke et al, 2006).
Indeed, a median PFS of 1.9 months was seen in the placebo-treated control arm of a trial accruing a similar population of RCC patients (Motzer et al, 2008).
Acute and late ⩾ grade 3 neurological toxicities (NTs) were analysed among 2761 patients from 14 RTOG trials accrued from 1983 to 2003.
Each of these trials accrued approximately 50000 subjects, who are in stages of clinical and imaging follow-up.
206 Thus, many trials accruing few participants and reporting large treatment effects may have been stopped earlier than planned but failed to report this action.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com