43 For systemic safety, the results showed a slightly higher trend risk of stroke in the 0.5 mg versus 0.3 mg group (1.2% versus 0.6%), but the difference was not statistically significant.
Community surveys carried out in some parts of Ghana reported high prevalence of some stroke risk factors particularly hypertension 19-488%) [ 13, 14], which may partly explain the trend of increasing stroke cases in the country.
20– 23 In Ghana, there is a high prevalence of hypertension in the general population, which may partly account for the trend of increasing stroke cases in the country.
The heart rate was significantly lower in the treatment group (P < 0.05), which associated with a trend of increased stroke volume and cardiac output.
The trend between year of stroke and receipt of rehabilitation therapy or speech and language therapy was significant (P<0.001).
Temporal trends of characteristics of stroke patients, comparing groups A and B, are summarised in table 2 and HRs for death, comparing the two groups, are summarised in table 3. The characteristics of stroke patients in groups A and B are summarised in online supplementary table S3.
Also, the patterns of the trend of CHD and stroke incidence have been shown to vary in a population [ 12, 17].
We have therefore performed separate analyses on the trend of BP and stroke and IHD mortality in individuals of the same age groups as those who had salt intake measured.
