Exact(2)
These "hyper-parameters" describe the overall trend of selection across a group of loci indicating whether these loci as a group are experiencing positive or negative selection.
The MKPRF approach is based on a hierarchical Bayesian model which can describe not only the strength and direction of selection at individual loci but also an overall trend of selection across a group of loci.
Similar(58)
The wood quality and drought tolerance candidate loci were not in general under positive or negative selection, but the non-conserved disease candidate loci showed a clear trend of positive selection overall.
While a trend of positive selection on plant size was detected in both ranges (though higher in the non-native area), positive selection on relative resistance was only detected in the native region, supporting our fourth prediction.
The results showed a general trend of reduced selection by the 200-mesh circumference and thicker twined codends, and especially by the industry-preferred 200-mesh circumference codend constructed from 5-mm diameter twine.
Ago1 protein conservation indicates an evolutionary trend of purifying selection, probably due to conserved mechanisms in developmental pathways.
Conclusive evidence for a general trend of positive selection was not found for the set of genes, since nearly all ω values were much less than one, though there were a few higher post-duplication values that suggested some duplicates may have been influenced by directional selection.
Table 3 moreover illustrates a general trend for selection in favour of heterozygotes: compared to the expectation, there are persistently less observed homozygotes (38Ser, 38Gly) and more observed heterozygotes (Gly38Ser) in Central Europeans, Han Chinese, and Yoruba.
Finally, it is worth to note that Japanese from Tokyo represent the only exception from the general trend for selection in favour of heterozygotes: expected and observed genotype counts are the same with respect to homozygotes and nearly identical regarding the heterozygotes.
The degree analysis for all three populations combined showed a similar trend: the signals of selection were underrepresented in the lower range (DC 2 3, nominal P = 0.01), but were mildly enriched in the intermediate to high range (DC 10 20, nominal P = 0.054).
We aimed to determine outcomes after LDP at a specialized center, analyze trends of patient selection and operative technique, and validate a complication risk score (CRS).
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