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Following trauma a tremendous inflammatory response occurs (Systemic Inflammatory Response Syndrome - SIRS[ 4]) and almost simultaneously, an appropriate and extremely important counter inflammatory response is initiated (Compensatory Anti-inflammatory Response Syndrome -CARS[ 5]).
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On this basis, the conception of the immune pathophysiology of sepsis dramatically evolved and now encompasses both an initial tremendous systemic inflammatory response responsible for organ failures and a compensatory anti-inflammatory response with multiple immune defects that may result in complex immunosuppression in some patients [31].
On this basis, the conception of the immune pathophysiology of sepsis dramatically evolved and now encompasses both an initial tremendous systemic inflammatory response responsible for organ failures and a compensatory anti-inflammatory response with multiple immune defects that may result in complex immunosuppression in some patients [ 31].
This prevented an inflammatory response.
That sustained inflammatory response characterizes autoimmune disease.
Another stress response pathway triggers a branch of the immune system known as the inflammatory response.
That injury can, in turn, trigger a normal inflammatory response that produces scarring.
"If you do anything to the pancreas, you initiate an inflammatory response," Dr. Liddle said.
The cytokines, which cause a useful inflammatory response in small doses, are lethal en masse.
But in a weakened patient, that inflammatory response itself can be dangerous.
The drug triggers an inflammatory response that drives out the hepatitis virus.
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