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As expected, the genetic architecture of these complex traits, shows tremendous complexity, and the discovery and characterisation of susceptibility alleles constitute a real challenge for the geneticist.
However, meso-scale modelling usually means tremendous complexity and long computational time.
The administrative agencies that were created during Franklin Delano Roosevelt's New Deal were a response to the tremendous complexity and growth of the national economy.
He's by no means the only reason for watching: Pilar Lorengar is immensely touching as Elisabeth; Patricia Johnson makes Eboli a figure of tremendous complexity; and there's grand, intense conducting from Wolfgang Sawallisch.
Because of its tremendous complexity and elicited immune responses, the vaccine design should considered multiple antigens to enhance immune-protection, involved in the different stages of pathogenesis besides inducing a specific immune response by B- and T-cell multi-epitopes.
"I was blown away by the tremendous complexity and amazing diversity" of forests, he says.
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"While there's this amazing opportunity to avoid the wealth transfer taxes of people who died in 2010, there is tremendous family complexity and tremendous downside to this boondoggle".
This adds tremendous complexity to product and process design, which this paper shows by using the automotive sector as a particularly challenging example.
All of these regulatory steps affect the function of individual CBX protein and allow for tremendous complexity in PRC1 activity and sequence specificity.
Although it may seem surprising at first glance, the performance gap has been widening over time, due to the tremendous complexity increase in microprocessor and memory architectures, and to the rising level of abstraction of popular programming languages and styles.
Our results complement recent findings by the ENIGMA consortium, demonstrating that BRCA1 AS, despite its tremendous complexity, is similar in breast and blood samples, with no evidences for tissue specific AS events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com