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"tremendous breakthrough" is a correct and usable phrase in written English.
It can be used to describe a significant breakthrough or achievement. For example, "This new research has been a tremendous breakthrough in understanding the complexities of the human brain."
Exact(18)
"It's a tremendous breakthrough with huge implications for molecular biology and molecular genetics.
Tommy Nilsson, party manager for southern Sweden, said the poll was a "tremendous breakthrough" for the party.
"It was the world's original instant-news war, made possible by the telegraph -- the 'lightning,' they called it -- a tremendous breakthrough in communications technology".
And we've improved on multitouch with 3D touch, a tremendous breakthrough in interacting with the smartphone," said Phil Schiller on stage.
The girls do fall out over the bin thing, but the fact that they avoid physical meltdown is hailed by all as a tremendous breakthrough.
The first detections of gravitational waves constitute a tremendous breakthrough in fundamental physics and astronomy: they are not only the first direct detections of such elusive signals, but also the first irrefutable observations of black-hole binary systems.
Similar(42)
At the same time the field was declining, there have been tremendous breakthroughs in the brain sciences.
However, while tremendous breakthroughs and technological innovations continue, maneuvering through highly innovative research and development into regulatory approval and commercialization of valuable animal biotechnology products that are needed and wanted by consumers, physicians, and patients is challenging.
Although tremendous breakthroughs in cardiovascular diagnostics and cardiothoracic surgery have been achieved over the past century, leading to increased survival for newborns with CHDs, the etiology of most congenital heart defects remains unknown.
Deep Learning enabled tremendous breakthroughs in visual understanding and speech recognition.
Already there have been some tremendous breakthroughs with the approval of GeneXpert, a new rapid diagnostic, and bedaquiline, the first new antibiotic for TB approved in 50 years.
More suggestions(15)
tremendous breakout
tremendous headway
tremendous triumph
tremendous milestone
tremendous success
tremendous turnaround
incredible breakthrough
substantial breakthrough
huge breakthrough
remarkable breakthrough
great breakthrough
massive breakthrough
phenomenal breakthrough
tremendous progress
immense breakthrough
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com