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In contrast to the aneurysmal segment, the arterial tree of patients with AAA display higher 18F-FDG uptake [18].
Phylogenetic analysis revealed marked compartmentalization of the HIV-1 quasispecies between the monocytes and the CD4+ T-cells in all six patients (the phylogenetic tree of patients 18 and 29 are shown in Fig. 1A and 1B; Fig. S2 in the supplemental material gives the sequence alignments).
Both inflammation and structural changes (referred to as remodeling) occur in the tracheobronchial tree of patients with asthma.
The sensitivity of BALF GM may be higher than that from serum because of the high fungal burden in the bronchial tree of patients with IPA.
We agree that the construction of phylogenetic trees is a good option to infer temporal orders of gene mutations by assuming common ancestors are early events, but limited to the fact that only very few genes have been considered in this study, it is difficult to reconstruct an accurate phylogenetic tree of patients.
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For example, the phylogenetic tree of patient #1 (Author response images 6 and 7) indicates del13q and delRB1 are early events, and then two branches are independently developed with one harbors SF3B1 K700E) and del11q, and the other harbors SF3B1 K666E).
Phylogenetic trees of patients with two sequenced tumor samples.
Similarly, organoids from an Alagille syndrome patient reproduce the structural duct defects present in the biliary tree of these patients.
A family tree of the patient showing the mode of inheritance of the mutation is shown in Figure 1.
The outcomes considered in the decision tree are: deaths of patients who could not receive blood transfusions due to blood shortage and the number of HIV, HCV and HBV infections.
A specialist in fetal medicine, he meets with families who have a history of genetic diseases, collects blood samples and draws up the detailed family trees of his patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com