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These treatments were randomised within six complete blocks at the University of Oxford's farm at Wytham.
Treatments were randomised using a computer generated list in balanced blocks of 10.
All treatments were randomised.
To minimise the effect of time, treatments were randomised for each polyp.
Patients' radiotherapy treatments were randomised between (a) total dose of 74 vs 64 Gy; (b) treatment margin (GTV-PTV) of 1.0 vs 1.5 cm.
The bleomycin and saline control treatments were randomised between the most caudal segments of the left and right caudal lobes in different sheep.
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The order of treatments was randomised for each fish within each experiment.
The order in which each patient received the treatments was randomised.
Patients with active RA despite previous TNFi treatment were randomised to receive abatacept, rituximab or a different TNFi.
In stratum two, hysterectomised women who were only prepared to take active treatment were randomised to estrogen only HRT or combined HRT using a block size of 16.
In 1983, a new trial was initiated, in which recurrence-free patients, after 2 years of tamoxifen treatment, were randomised to 3 more years of tamoxifen or no further therapy.
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