Sentence examples for treatment we next from inspiring English sources

Furthermore, since we have previously observed increased expression of PD-1 on tumor-infiltrating CD8+ T cells following α-4-1BB/α-OX-40 α-4-1BB/α-OX-40 α-4-1BB/α-OX-40 α-4-1BB/α-OX-40 α-4-1BB/α-OX-40witreatmentn agonist immunotherapy regimen (α-4-1BB/α-OX-40) and blockade weth α-PD-1 anextody.

Because distinct mutants of PML-RARA exhibited different AS2O3 binding affinity and degradation pattern followed by AS2O3 treatment, we next detected whether these mutants affect the basal SUMOylation of PML-RARA.

To characterize the DNA damage pathway activated by DBD plasma treatment, we next sought to identify the kinase that phosphorylates H2AX in response to DBD plasma treatment.

Having determined that mitochondrial oxidative stress causes hyperphosphorylation of tau, and that this can be ameliorated by antioxidant treatment, we next asked if there might be a synergistic interplay between aberrant amyloid metabolism and mitochondrial oxidative stress.

Because epithelia mainly secreted IL-6 and IL-8 into the supernatant in response to poly-l-arginine treatment, we next determined the concentrations of IL-6 and IL-8 secreted by the epithelia.

Having demonstrated that pERK signalling recovered after PLX4720 treatment, we next determined whether dual BRAF/MEK inhibition led to enhanced cytotoxicity.

As we aimed to explore whether we indeed induce a wrong differentiation track with long treatments, but not with short treatments, we next compared the differentially expressed PS that are induced by short, medium, and long treatment with TSA.

Having established the effectiveness of CHX treatments, we next examined the transcriptional responses of twelve Group A genes (nine in the up-regulated class and three in the down-regulated class) and one up-regulated Group B gene following combined DEX/CHX exposure.

Having demonstrated enhanced engraftment and humanization of the mouse mammary fat pad by exposure to estrogen and human macrophage injection, without observing an altered histology of the humanized areas between different treatment groups, we next asked if a combined macrophage/estrogen treatment might influence overall cellular growth or enhance the invasiveness of human fibroblasts.

As the previous analyses identified calprotectin, hs-CRP, IL-6 and MMP-3 as the most promising biomarkers of treatment response, we next assessed their potential to change upon active treatment by using the SRM, which reflects the ability to detect changes over time [ 32].

To study the possible complementarity of both treatment modalities, we next combined 4 Gy IR with 20  μg sunitinib using three different treatment schedules.