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In the CAMERA study, patients were randomly assigned to either an intensive tightly controlled MTX-based treatment strategy based on computer-guided monthly predefined response criteria or to a conventional MTX-based treatment strategy based on regular clinical practice with 3-monthly visits.
We constructed a treatment strategy based on the location of the soft tissue defect and the perforator anatomy for expedient wound coverage in 1 stage.
Based on a generic architecture, the PANDEX prototype, which focuses on the domain of genetic prenatal consultation, is designed to calculate the optimal treatment strategy based on the patient's clinical data and preferences.
A treatment strategy based on CDDP monotherapy and surgery thus appears effective in SR-HB but, despite CT intensification, only half of the HR-HB patients are long-term survivors.
Generation of pancreatic β-cells from human pluripotent stem cells (hPSCs) has enormous importance in type 1 diabetes (T1D), as it is fundamental to a treatment strategy based on cellular therapeutics.
Hence, the proper imaging diagnostic tool to discriminate patients with local recurrence from advanced metastatic PCa is essential to select the most adequate treatment strategy based on the spread and anatomical location of the disease.
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Cancer treatment strategies based on immune stimulation have recently entered the clinical arena, with unprecedented success.
Antimalarial treatment strategies based on in vitro studies are limited by the paucity of pharmacodynamic information for dosage regimen design.
A model that accurately captures serial colonoscopy results could potentially be used to design and evaluate post-colonoscopy treatment strategies based on the risk of individual patients.
All these molecular pathways are involved in RCC biology, tumorigenesis, and progression, and serve as the source of new rational treatment strategies based on the design of small molecule inhibitors directed against their targets.
Although novel treatment strategies based on the gene therapy approach for epilepsy has been encouraging, there is still a gap in demonstrating a proof-of-concept in a clinically relevant animal model and study design.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com