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Treatment sequences were assigned randomly to cows.
The diagnosis, planning, appliance design and treatment sequences are described.
The authors analyze the cost-effectiveness of rituximab as second biologic agent in different treatment sequences.
Fifty-four patients were assigned to one of the two treatment sequences.
Treatment sequences were assigned alternately to cows based upon date of parturition.
A total of 74 patients were randomised to 1 of 4 treatment sequences.
Chambers were assigned to dietary treatment sequences in a single 4 × 4 Latin square design.
A method for adaptively allocating new subjects to treatment sequences in repeated measurements designs is given.
Wu et al. [56] report the only cost-effectiveness model found for China comparing seven different treatment sequences.
Animals were housed in 9 pens and assigned randomly to treatment sequences in a 3 × 3 Latin square design.
These randomized switches generate treatment sequences that provide complete or partial data on adaptive treatment strategies of interest.
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