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The involvement of different CYPs in the metabolism, elimination, and bioactivation of oxycodone makes the treatment sensitive to clinically meaningful DDI leading to altered analgesic or adverse effects profile.
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These five concepts were selected based on their perceived sensitivity to change in disease status, either by progression or treatment, and sensitive to treatment effects.
Blocking this process of methylation could be important since this could lead to patients who are resistant to hormone treatment becoming sensitive to hormone treatment [ 18].
However, it is also found that in certain critical conditions, such treatment is sensitive to reduced velocity, and may amplify the interference effect and result in larger displacements.
However, all PrP released from cells within 1 hour of treatment was sensitive to digestion with proteinase K.
After imatinib treatment, patients sensitive to imatinib (SCML) and patients resistant to imatinib (RCML) had similar metabolic phenotypes to those of healthy controls and UCML, respectively.
Cell lines resistant to agents used in ovarian cancer treatment remained sensitive to methotrexate.
The H1N1 virus isolated before the patient received oseltamivir treatment was sensitive to oseltamivir.
The fold-change of tumor free VEGF in response to the treatment is sensitive to expression of VEGF receptors and co-receptors.
This is particularly valuable when the optimal choice of treatment is sensitive to a patient's views about the seriousness of potential complications or outcomes.
The results reveal that treatments are costly and treatment costs are very sensitive to treatment types used and timing of the treatment conducted.
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