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The observed increased expression of PD-L1 related to oxaliplatin treatment implicates undesired effects on the immunological elimination of tumor cells outcome in cancer patients.
Although we did not focus on which apoptotic pathway was induced by BT, decreased mitochondrial transmembrane potential following BT treatment implicates the intrinsic (mitochondrial) pathway.
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The solid-state kinetics was captured by a contracting volume model and Arrhenius treatment implicated the occurrence of a 'compensation effect' for the carbothermal synthesis.
Expression of several genes that regulate glycerolipid synthesis was not changed by GW7647 treatment, implicating involvement of other targets to explain the TAG-depleting effect of the compound.
We observed an increase in the frequencies of MDSCs in mouse spleen and liver at early stage of ConA treatment, implicating that the MDSCs might be involved in the initial resistance of mice against ConA-mediated inflammation.
We here report a systematic detection of transcriptome changes in response to oxidative signals generated in leukemia cells upon fenretinide treatment, implicating the occurrence of numerous stress-responsive events during the fenretinide induced apoptosis, such as redox response, endoplasmic reticulum stress/unfolded protein response, translational repression and proteasome activation.
Similar spatial changes were obtained with endogenous TSPs after cytochalasin D treatment, implicating physiological relevance.
Furthermore, intracellular free Ca2+ was increased after staurosporine treatment, implicating the presence of Ca2+-mediated effectors in nucleosomal release.
In the present study, the PKGII inhibitor did not influence the levels of NO and PGE2 release following CNP and/or IL-1β treatment, implicating alternative mechanisms.
We found that vesicle formation at self-contact sites was sensitive to cytochalasin D treatment, implicating a role for F-actin polymerization in this process.
Twenty-nine of those genes were differentially expressed 19 days after cessation of treatment, implicating them in the persistent milk yield response.
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