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Initial clinical translation studies like the current pilot study are not intended to provide conclusive proofs, but rather form an important step in a treatment development process and must be interpreted in this context.
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In Arabidopsis, a high level of FLC represses expression of both FT and SOC1, and it can be released by vernalization treatment or autonomous development process [ 1].
To further corroborate the view that expressions of carbohydrate, cell wall, and lipid metabolism-related genes were significantly altered by MES treatment during anther development process, detailed alternations of gene expressions were further analyzed in Ls, SBs, and An-MBs.
Given the hypoxic conditions commonly prevalent in the core of solid breast tumours, these findings have clear clinical implications for both treatment, and the drug development process.
With the realization of the importance of drug efflux transporters in disease processes and treatment, development of inhibitors to these transporters has been sought for use as adjuncts to therapy.
There is convergent evidence that overproduction, aberrant aggregation, or decreased elimination of different forms of amyloid beta protein (Aβ) are critical events in the pathogenesis of AD and, therefore, treatment development has focused on these processes.
Issues of tailoring highlight debates about the role of preferences and choice in access to mental health treatments [ 66], the tension between providing standardised treatments favoured by the clinical guideline development process, and the role of health services in meeting the personal preferences of patients.
The changes of sarcomere development process in ATR treatment were observed in the experiment at first.
The health care professionals work with patients so they are mainly exposed to symptoms and signs of disease and to treatment outcomes rather than to the development process of the disease especially for non-communicable diseases such as cancer.
Speeding up the research and development process means getting new treatments on the market sooner and saving lives.
Therefore, the fDM imaging biomarker for early prediction of treatment efficacy can be used in the drug development process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com