The treatment bundle, therefore, includes immunotherapy and surgical tumor resection, if applicable.
Despite these interventions, most patients still do not receive the full recommended treatment bundle.
Intervention: One year of targeted education focused on a four-element treatment bundle consisting of lung protective ventilation, early enteral nutrition, standardization of antibiotherapy for hospital-acquired pneumonia and a systematic approach to extubation.
We assessed demographic data, SAPS3 and compliance with sepsis treatment bundles and followed all patients until hospital discharge, truncated at 60 days.
Although our mortality rate was in the range of the Western world, it will be very interesting to see the effect of sepsis treatment bundles advocating for early recognition, aggressive hydration, and early antibiotics on sepsis-related mortality.
First, the Rivers protocol led to the implementation of limited sepsis treatment bundles resulting in a mortality decrease.
The need for treatment bundles for postresuscitation care and the foundation of cardiac-arrest centers have recently been discussed intensively [ 18].
Twelve months after the institutional Surviving Sepsis Campaign implementation and current use of the respective treatment bundles, this medical center adopted a standardized hospital maneuver to anticipate the identification of two or more suggestive infection signs.
A one-page SCR was derived from surviving sepsis guidelines, to prompt recognition of sepsis syndromes, comprehensive secondary assessment, initiation of resuscitation and antibiotic treatment bundles, and appropriate specialist consultations.
Fifth, look at all the hemodynamic optimization trials… Notwithstanding the disappointing results of follow-up studies, the original studies were important because they increased recognition of septic patients, led to more original ideas [ 5], and to effective treatment bundles not funded by third parties [ 6].
With regard to the role models of acute coronary care units, stroke-, tranda-, and burn-injury centers, specialized cardiac arrest-care centers, as well as predefined treatment bundles for the postresuscitation period have become a subject of discussion recently [ 16- 24].
