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The agents had to be added to an existing antidepressant regime with the aim of achieving an improved clinical response to an ongoing antidepressant treatment (augmentation) or an earlier onset of effect when starting antidepressant and augmentation agent simultaneously (acceleration).
A patient-centered approach could discern the most likely possibility and would then, as appropriate, address patient barriers to non-adherence (using behavioral interviewing methods such as motivational interviewing) or help facilitate choices among treatment augmentation options (using methods such as shared decision-making).
OCD checking may respond to treatment augmentation with D2/3 receptor antagonists.
Thus, future studies could target both prevention of mental and comorbid physical illness, focusing on disparity and somatic treatment augmentation.
Studies of MDD that focused on relapse prevention, treatment augmentation or treatment-resistant cases were also excluded, as these studies would have introduced additional heterogeneity into this evaluation.
The first category was a "treatment augmentation," defined as the presence of a claim for methotrexate, an anti-TNF agent, or natalizumab (a "new maintenance treatment") occurring alongside continuous 6-MP/AZA treatment, allowing for a 90-day grace period.
Similar(51)
Given the potential resemblance of EOLPs to the superfluous, non-functional checking behaviour in OCD, one could tentatively suggest that SRI-treatment augmentation with dopamine D2/3 receptor antagonists might be most beneficial for patients with excessive checking, but may promote checking behaviour in patients with previously low checking symptoms.
The vast majority of patients (91%) were women, with the most popular treatment breast augmentation, followed by eyelid surgery and then face/neck lifts.
This requires new treatment and augmentation approaches to be developed.
We have demonstrated that one year metformin treatment improves augmentation index in patients with nonalcoholic fatty liver disease.
Available strategies to address incomplete response to antidepressant monotherapy include maximizing initial therapy, neuromodulation, switching treatments, and augmentation.
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