Sentence examples for treating variants from inspiring English sources
An alternative to treating variants differently according to such factors as their rarity and predicted function would be to adopt a more post hoc, model-fitting approach which would attempt to make inferences about the nature and magnitude of the effect of each variant, though again it might be challenging to implement this in practice.
Contrariwise MTT assay revealed that oxidoreductase activity is decreased in all five treated variants.
Should we treat variants in well-characterised genes in the same way as those in pseudogenes or non-genic regions of the genome?
Within cells, the number of vacuoles was reduced and small vesicles appeared in the perinuclear cytoplasmic zone but malformed cells were present in all treated variants.
After washing out the additives and incubating for another 24 h, the oxLDL-treated cells retained much of the Oil Red O-stainable material and assumed the characteristic foam cell morphology, whereas the other treated variants were essentially indistinguishable from the untreated control.
The researchers are still studying how the drug affects particular groups such as pregnant women and those with the less common but harder to treat variant of sleeping sickness.
In the recent paper [ 1], the authors treat variant pathogenicity in a given patient as the unknown parameter.
These tests were performed treating all variants equally as well as with individual variants weighted by a measure of predicted functional consequence.
This method aims to infer causality of a genetic variant on expression of a gene by treating genetic variants as randomized variables and leveraging the causality equivalence theorem to identify the direction of effect.
In situations, such as clinical workflows, where FNs are very problematic and FPs less so, treating all variants in the high-confidence region as PASSing might be a good tradeoff.
The bottom line is that for decades the Clinic has been promoting a clinical approach to treating gender variant children and adolescents based upon a desire to promote the cisgender heterosexual norm using the confusion of research results generated by the deliberate conflation of trans kids with gender variant gay and straight ones.
