Sentence examples for treated on demand from inspiring English sources

Three (17.6%) subjects (ITT) on prophylaxis experienced no bleeding episodes, whereas none treated on demand were bleeding episode-free.

Three prophylaxis subjects who were treated on demand prior to study entry had >85% reduction in AsBR compared to the bleeding rate prior to study entry.

Minimal differences were seen between patients who started secondary prophylaxis at ≥12 years of age (group 4) and patients treated on demand (group 5; Table 4).

Over a 1-year period, 17 subjects were treated prophylactically (85 ± 15 U kg−1 every other day) while 19 subjects were treated on demand.

Therefore, the probability of death in each year for individuals treated on demand and with primary prophylaxis was based on a single Italian male life-table.

However, patients receiving secondary prophylaxis (initiated after several joint bleeds have occurred) also have less joint deterioration than those treated on demand [ 13].

Initially, long-term use of PDE5 inhibitors was recommended in patients who did not respond when treated on-demand.

Furthermore, the results support that the switch to prophylactic treatment is a potential key driver for improvement of HRQoL in patients with haemophilia who have earlier been treated on-demand.

Of the haemarthroses that occurred in subjects treated prophylactically, most were in existing target joints, while the majority of those in subjects treated on-demand were in new target joints.

The prophylactic dose and dosing regimen was based on a review of literature on the use of FEIBA in the prevention of bleeding in patients with haemophilia A with inhibitors to FVIII 5– 7. The primary outcome was a reduction in the annualized bleeding rate (ABR) among subjects on prophylaxis as compared to those treated on-demand over a period of 12 months ± 14 days.

Since sildenafil was first introduced to treat ED, on-demand administration was the recommended mode of its administration and this became the standard.