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From a clinical perspective, it is important to exclude treatable agents, such as Herpes virus and Cryptococcus in all patients.
Appropriate assessment is necessary to exclude treatable agents and identify pathogens warranting public health interventions, such as those transmitted by mosquitoes and those that are vaccine preventable.
If no diagnosis is made after completion of screening tests for common or treatable agents and evidence of regional WNV or other arbovirus activity exists, a second stage of testing might include arbovirus IgM ELISA of acute- and convalescent-phase specimens.
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Our findings, however, are of diagnostic and clinical relevance especially in patients with a severe course of viral gastroenteritis, since a second – potentially treatable – agent may enhance disease severity.
Other treatable etiological agents, Chlamydia pneumoniae and Mycoplasma pneumoniae, accounted for 11% in children and 8% in adults and with the same prevalence between patients with FP and OND.
Indeed, this phenotype characterized by decreased density and high remodeling at subchondral bone defines a subgroup of patients treatable with specific agents.
Whether the increase in myocardial autophagic activity after MI is impaired by DM and whether such an impairment, if any, is treatable by pharmacological agents have not been clarified.
If we consider Legionella spp., Mycoplasma pneumoniae and Chlamydophila pneumoniae as the three atypical bacterial pathogens treatable by antibacterial agents, it appears that only Legionella spp. are associated with a relevant mortality.
Actionable genetic alterations that are treatable with therapeutic agents have been identified in approximately 50% of lung adenocarcinomas and include mutations in EGFR, ERBB2, KRAS, ALK, BRAF, PIK3CA, AKT1, ROS1, NRAS, and MAP2K1[ 4].
In total, 37% of the gastric cancer population may be treatable by RTK/RAS targeting agents.
Seventy percent of breast cancers are estrogen receptor (ER -positive, and arER -positivepresumed to be hormone-responsive and potentiarey therefore or presumedble by anto-estrogenic agents.
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