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When using BFP to treat defects induced by a malignant tumor, postoperative radiation therapy should be considered.
The sural fasciocutaneous flap is able to bring excellent trophism to the acceptor site and may be successfully employed to treat defects of the proximal third of the foot and the lower leg [10, 11, 12, 13].
The aim of hard tissue regenerative medicine in the field of dentistry is to treat defects of the alveolar and/or jaw bone originating from diverse etiologies.
To treat defects such as osteoporosis and bisphosphonate-related osteonecrosis of the jaw (BRONJ), cancellous and cortical autologous bone grafts are the gold standard [ 4].
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This allows discriminators to treat defecting on defectors as a good thing rather than a bad thing.
Caveolin-1 staining in capillary-like structures showed a 1.16 1.38 fold increased expression in PHB treated defects compared to controls.
Immunostaining with an antibody against type-II collagen showed the diffuse presence of the repair cartilage in the IGF-I treated defects.
The white arrows mark the defects Fig. 5 MRI and corresponding CT for the empty osteochondral defects (a and d), autologous bone graft (b and e) and the ADTT treated defects (c and f).
Figure 6 Histological sections stained with Safranin O. A) Fibrocartilagenous repair tissue typical of that seen in empty defects, scaffold alone and BMP-7, B) Hyaline cartilage-like repair tissue typical of that seen in scaffold + rhFGF-18 treated defects.
Eighty radial bone defects were bilaterally created in 40 Sprague-Dawley rats and were randomly divided into eight groups including untreated, autograft, CS, Gel, CS-PG, Gel-PG, CS-Gel, and CS-Gel-PG treated defects.
We believe that external fixation is an effective technique for treating defects, problems and complications related to benign bone tumours or the effects arising from wide excision of the primary lesion.
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