The companies say they have a generally safe record in treating a difficult disease and are fighting lawsuits in which some patients claim harm.
Achieving ideal results when treating a difficult malocclusion is a challenge that orthodontists frequently encounter.
At best, that argument treats a difficult, complex issue as being far more settled than it really is.
For example, when treating a difficult airway, the CDSS provides an optional algorithm over airway management in 5 steps.
Cell encapsulation holds great promises in regenerative medicine to treat a range of difficult diseases, including type 1 diabetes, tumor, heart failure, and neurodegenerative disorders.
When three-quarters of the patients drop out, all that is demonstrated is that you're treating a very difficult population.
Celgene's drug Abraxane prolonged the lives of patients with advanced pancreatic cancer by almost two months in a clinical trial, researchers reported Tuesday, signifying an advance in treating a notoriously difficult disease but not as big a leap as some doctors and investors had hoped.
"It is really difficult to treat a disease when you do not understand what causes it," one of the lead researchers, Prof Julie Williams from Cardiff University, said.
It is often more difficult to treat a pathological fracture than a traumatic fracture.
An additional factor considered was that it would be very difficult to treat a recurrence if one were to occur.
