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These studies led to the suggestion that B cells may represent an important link between trapped virus on FDCs and virus replicating in CD4+ T cells.
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It is also important for trapping viruses and bacteria for other scientists to study and treat.
Inside their crystal structure, GTCHC complexes can trapped a virus (Figure 7D) an anomalous lipoprotein (Figure 7E), or a malignant cell, and they disintegrate it.
We show that the mucus, which was still present in the explant culture substantiating the physiological relevance of the model, had trapped numerous virus particles (Fig 5B and C).
Flosstradamus weren't patient zero for the trap virus that spread across the mega-fests in the early 10s, but they did seem to understand its dynamics better than just about anyone else.
Earlier studies reported that DC present at the site of infection trap virus particles via DC-SIGN and transfer the virus to the interacting naïve T cells.
We confirmed efficient infection by analyzing the fluorescence of a promoter-less EGFP reporter that is encoded by the gene trap virus (Jae et al., 2014).
Haploid cells were infected with gene trap virus as previously described (Jae et al., 2014) and plated on 10 × 145 cm dishes.
Distribution and orientation of gene trap virus insertions were, furthermore, consistent with a high likelihood of inducing loss-of-function mutations.
To identify genes affecting platinum drug sensitivity, we performed genomewide loss-of-function screens of haploid KBM7 cells that were subjected to insertional mutagenesis using a gene-trap virus (Carette et al, 2009) (Fig 1A).
Cold weather also forces people indoors more often where it's easier to be trapped with viruses.
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