Sentence examples for trap cleavage from inspiring English sources

Acting much like a molecular "mouse trap," cleavage of the sulfur-sulfur bond is thought to trigger a chain of events culminating in formation of a phenylene diradical, which removes hydrogen atoms from deoxyribonucleic acid (DNA).

Finally, DNA cleavage induced by the drug metabolite was reversed when the active site Mg2+ ions were chelated with EDTA or the reaction mixture was treated with 0.5 M salt prior to trapping cleavage complexes with SDS.

Nuclear extracts with high topoisomerase I activity from HepG2 cells and a surgically removed hepatoma were used to assess the inhibitory potential of commercial heparin, normal liver HS, human hepatocellular carcinoma, and peritumoral liver tissue GAG specimens on topo I plasmid relaxation and TpT-trapped cleavage reaction.

H2DCFDA can easily diffuse into cells and is trapped after cleavage of H2DCFDA to H2DCF by intracellular esterases.

Recent studies using laser microsurgery have proposed that Aurora B inhibits completion of cytokinesis when there is chromatin trapped in the cleavage furrow.

The same pattern was also observed after treatment with camptothecin, a Topoisomerase I inhibitor that induces DSBs in S-phase when replication forks encounter trapped Top1-DNA cleavage complexes.

Chromatid arm shortening that occurs in early anaphase to prevent chromatin from being trapped in the cleavage furrow, is most evident in chromosomal arms that are close to the spindle midzone, and appears to depend on the pool of Aurora B present on the midzone microtubules (Mora-Bermudez et al. 2007; Neurohr et al. 2011).

Furthermore, the FluoZin-3 AM variant is membrane-permeable and trapped in cells upon cleavage of the AM groups by esterases.

(3) The side chain of L837 in CL1 (L856 in BAI3) at the cleavage site is trapped in a conserved hydrophobic pocket (Supplementary Figure S3B).

DNA cleavage complexes were trapped by the addition of 2 μL of 5% SDS followed by 1 μL of 375 mM Na2EDTA (pH 8.0).

Enzyme DNA cleavage complexes were trapped by adding 2 μL of 5% SDS followed by 2 μL of 250 mM EDTA (pH 8.0).