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The transposition rate is modulated by regulation of active TE copies.
However, note that here the insertion rate will be defined per base pair whereas the transposition rate is normally given per transposable element.
The transposition rate is not necessarily constant, it may be affected by various regulation mechanisms, or by the progressive loss of transposition activity by mutation accumulation on TE sequences.
A putative low transposition rate is however not reflected by the expression level of Cocv5, which is the sixth most abundant TE family in the RNASeq database (tables 1 3).
As for IS3, it is possible that its transposition rate is in fact lower than that of all the others, because all five copies of this element were functional in the ancestral genome, as determined by sequencing.
With an initial IS distribution with a low mean copy number [ 62], we find that ISs gradually go extinct in the population, and the process of IS elimination is slower if positive selection on beneficial mutations is strong or if the transposition rate is low.
Similar(53)
The transposition rate was measured as described in the prior study18.
The transposition rate was determined by dividing the galactose colony count by the total number of cells plated.
Matsuda and Garfinkel (2009) showed that antisense RNA copies of Ty1 in Saccharomyces can inhibit transposition; therefore, the high expression of Cocv5 and its putative low transposition rate are not incompatible.
The step change in transposition rates is shown as a vertical line at the 5000 t h generation.
Under the second scenario (burst, no regulation), a transposition burst event occurs (δ>0) at time t= T and transposition rates are permanently elevated from that time (dashed).
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