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This type of cut-and-paste transposition moves the transposon but does not increase the copy number; mechanisms involving replication of the transposon during transposition also exist among DNA transposons.
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When women are going to have pelvic radiotherapy, ovarian transposition (moving the ovaries out of the field to minimise their exposure) can often preserve hormonal function and fertility, though uterine capacity may still be damaged [152].
The absence of inlC in strains of lineage III may have been caused by a deleterious transposition moving two adjacent lipoprotein coding genes (lmo1264-5) by approximately 600kb to replace the internalin (Additional file 17).
Indeed, both require three events of transposition to move from PanGO (node 1) to the ant1GO (node 4), and both fully describe the observed GOs.
In ovarian transposition, ovaries are moved higher in the abdomen and away from the radiation field through surgical methods.
Active TEs encode the enzymes necessary for their transposition, either to move between nonhomologous regions in the genome or to copy themselves to other positions.
TC1-like elements typically transpose via double strand DNA breaks, and it may be possible that a transposase enzyme targeted the element for transposition but instead moved the larger SDR flanking regions throughout the genome.
When comparing genes between species, nonconserved duplicates have been deleted (referenced hereafter as PAV for presence/absence variation between species), duplicated in tandem (CNV for copy number variation between species), inverted, duplicated within a block or moved (transposition of one copy or SSD consisting in deletion of one copy and duplication of the other) in the course of evolution.
TEs represent a very diverse community of sequences that fundamentally differ in their mechanism of transposition: Class I retrotransposons move via "copy and paste" mechanisms using RNA intermediates, whereas Class II DNA transposons move via "cut and paste" mechanisms through DNA intermediates (Wicker et al. 2007).
Repeat sequences in other prokaryotes have been shown to be moved via transposition [7], [11], [15], [16].
To determine if p[ w +mC GM roX1 MS2-6] would be utilized for gap repair if situated in roX1, targeted transposition was used to move it to the plArB insertion site in roX1 mb710.
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