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Considering the data obtained in this study, IS 6110 is unarguably the species' most important mobile element when considering transposition impact on genomic integrity.
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SynFind is an important tool for assessing genome dynamics including gene transpositions, impact of genome duplications, and correlation to functional changes across a set of related taxa of interest.
Interest has been paid only very recently to the impact of transposition dynamics on structural variation (Lynch 2007).
The most obvious factor that affects the random integration of Mu DNA into bacterial genes is their efficient transcription, which has a clearly negative impact on transposition (Manna et al. 2004).
We also consider a second scenario where the population is initialised with a single IS element in a single cell, so that we can investigate the impact of transposition bursts on the initial invasion of IS elements.
However, the extent and impact of Helitron transposition and gene chimera formation across species has not been previously investigated.
This possibility may explain why extra cis sequences in Tol2ends-cassette has a greater impact in deregulating transposition activity than that of pXLBacII-cassette.
We also track the 5 % and 95%% quantiles of cell fitness in the population to examine the impact of IS transpositions on the organismal fitness.
Indeed the first order formalism developed here implicitly assumes that all changes to a DNA sequence that have resulted in the form that we observe now have taken place through mutational changes only, and recombinations and transpositions have not had any major impact on the sequences.
Although it is conventional to apply these criteria only to a "hominine" clade originating about six million years ago, the understanding of the impact of this septo-neural transposition event is a formidable challenge to that framework.
At the same time, accumulation of TEs in different subpopulations may eventually help them to "drift apart" due to their mutagenic impact driven by the rate of transposition, which can increase the probability of reproductive isolation due to genetic diversification.
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