Sentence examples for transposition activity from inspiring English sources

These transcripts may indicate active ongoing transposition activity in Æ. ægypti or, more likely, they may represent regulatory elements suppressing transposition of relatively recent genome invasions.

When an organism acquires a new active transposon, a burst of transposition activity may ensue until all copies are mutationally inactivated.

The genome of the green anole continues to sustain strong transposition activity while there are almost no active copies in the alligator anymore.

However, long-term maintenance of transposition activity is unlikely.

To test this hypothesis, we examined if the transposition activity, which has been experimentally validated in Corynebacterium glutamicum29, was also functional in proteobacteria.

Deletion of the terminal sequences including the sub-terminal repeats decreased the transposition activity of the 708-residue-long transposase, while the transposition activity of the short form of transposase was not affected.

We compared transposition activity of piggyBac with Sleeping Beauty (SB), a widely used transposon system for preclinical gene therapy studies.

Kwon D, Chalmers RM, Kleckner N. Structural domains of IS10 transposase and reconstitution of transposition activity from proteolytic fragments lacking an interdomain linker.

We show protein incorporation and proteolytic release of the DNA transposase within matured LNPs, resulting in high levels of DNA transposition activity in LNP-treated cells.

Transposition activity exhibited by N-terminal chimeras was increased to levels similar to native SB through the use of a hyperactive transposase (SB12) and activating transposon mutations.

An engineered piggyBac transposon with minimal length 5′ and 3′ terminal repeats exhibited greater transposition activity in transfected cultured human cells than a well-characterized hyperactive SB system.