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Detection of similar but mutated copies of both genes, NCU09968 and sly1-1, in Sly1-3 and Sly1-4 suggesthathathehentirere Sly1-1 locus transposed and not just the transposase, sly1-1.
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However, this could also reflect the fact that non-functional TEs can not transpose and are rapidly eliminated from the genome through deletions, therefore inducing a bias in the Ka/Ks ratio.
Domesticated transposons are not able to transpose, and for this reason they are in general present as single-copy genes and do not contain TIRs or TSDs.
In an attempt to detect factors associated with ulnar neuropathy, Wiggers et al. [19] diagnosed a 16% ulnar neuropathy, regardless of whether the nerve was transposed or not.
PB was shown to efficiently integrate and transpose randomly not only in cell lines but also in the mouse germ line.
A trend toward shorter exons, more indels and bigger maximum indel lengths suggests that transposed duplications are not perfectly copied and losses of DNA segments frequently happen.
The TIR sequences of five newly transposed copies are not perfectly conserved, but each TIR sequence contains an 8 bp motif "AACTAAAC (the complementary sequence "GTTTAGTT") (See additional file 7: Sequence alignment of the mGing elements from new transposition sites).
The presence of identical paralogous elements can be considered as strong evidence for current element activity (tables 1 3); short terminal branches indicate that a family has recently transposed, but do not provide any direct evidence that the family is currently active in the sequenced strains.
How much to localize the curriculum is an ongoing issue at the Education City schools, where officials sometimes find that problems and ideas transposed from America do not necessarily make much sense.
In the simulations, all copies are able to transpose (which does not necessarily mean that they are all capable of producing the transposition machinery).
This can happen if Member States do not transpose legislation and, of course, if it is not implemented correctly.
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