DOI: http://dx.doi.org/10.7554/eLife.04273.012 A different coupling stoichiometry for di- vs tri-peptides raises an interesting question of whether different amino-acid side chains within the transporter are required for di-peptide vs tri-peptide transport.
We found that heterologous expression of a lysine transporter was required to excrete lysine and avoid intracellular accumulation that correlated with poor fitness.
Our results suggest that co-expression of genes for UDP-GalNAc polypeptide N-acetyl-α-galactosaminyltransferase, UDpolypeptide N-acetyl-α-galactosaminyltransferase are required to achieve efficient polypeptide N-acetyl-α-galactosaminyltransferaseoteins.
The inability of non-transportable EAAT inhibitors to affect GABA transport in the rat cortical NPMV (Figure 1B) suggested that the translocation process through Glu transporters is required to evoke the GABA release.
It has been reported that bceABRS (also named as mbrABCD) system, encoding a two component signal transduction system and an ABC-transporter, is required for bacitracin resistance in S. mutans[ 63, 64].
Therefore, the discovery of novel pentose transporters is required.
Therefore, to design an effective chemotherapeutic regimen, thorough knowledge of the mechanisms of MDR caused by ABC transporters is required.
Because Zn cannot diffuse across cell membrane, specific zinc transporters are required to transport Zn into cytoplasm [ 12, 13].
