In the early 1960s the transporter concept originated as a method of reducing aircraft maneuvering on the apron and of eliminating the need for passengers to climb up and down stairways in order to enter or exit the aircraft.
The others include a commercial-grade cargo e-bike, an electric concept van called the Crafter HyMotion that's powered by hydrogen fuel cell system, a Transporter concept van with a 48-volt mild hybrid drive system that combines a turbodiesel engine with an electric drive and finally, the ABT e-Caddy, a small van that will to arrive on market in mid-2019.
The identification of ABA receptors is a great breakthrough in the field of ABA study, whereas the discovery of ABA transporter has changed our concept that ABA is delivered solely by passive transport.
One mechanism under consideration is transporter, target and metabolic concept.
As a proof of this concept, serotonin transporter genetic polymorphisms may predict risk for the common weight gain associated with clozapine administration [ 28].
The majority of proteins are involved in metabolic processes, such as energy metabolism and transporters, supporting the general concept that the core genome encompasses essential functions required for survival of the microorganism.
This paved the way for the discovery of a similar amino acid sensor (Didion et al., 1998; Iraqui et al., 1999a, b 1999b; Klasson et al., 1999) and firmly established the concept of transporter-like proteins being used as sensors for the nutrient they likely once transported previously in evolution.
In addition to the findings by Hilfiker et al. [ 35] that Slc34a2 protein is expressed on the apical membrane of mature enterocytes in the duodenum, we observed that Slc34a2 mRNA is villus-specific along the whole intestine except for the duodenum, reinforcing the concept that transporters expressed in the villi epithelium tend to be implicated more in absorptive processes.
Neuroimaging data shows an upregulation of transporters for monocarboxylic acid transporters in hypoglycemia unawareness, the concept being that because the neurons are better able to use lactate during hypoglycemia, there is less neuronal drive for counterregulation (28).
X. albilineans strain GPE PC73 encodes putative sugar transporter systems, further supporting the concept that cell-wall derived sugars are consumed by this pathogen.
The observation that cells selected for resistance to Cu or the Pt drugs display bidirectional cross-resistance, parallel defects in the transport of Cu and the Pt drugs and altered expression of Cu transporters is consistent with the concept that the Cu homeostasis proteins regulate sensitivity to the Pt drugs by influencing their uptake, efflux and intracellular distribution.
