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The two-dimensional model used in this work to analyze adsorption kinetics in PSi takes into account mass transportation and binding reactions between molecules in bulk solution and immobilized groups at the pore walls.
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As inhibitory activity was tested in intact cells, the result represents the cumulative effects of a compound's cellular transportation, metabolism and binding affinity to 11β-HSD1.
In this paper we have opted to use the C-terminal amino acid of CTL epitopes to position an epitope in a protein sequence, as the C-terminal amino acid is the most defining property of an epitope: amino acid substitutions at the C-terminal have a large effect on proteasomal cleavage, TAP transportation and MHC binding [ 23, 24] (Fig. 1).
For instance, mAbs elimination is generally dose dependent and mainly associated with FcRn transportation and antibody-antigen binding [ 33].
Collectively, gene expression data, relative to lipid metabolism, suggest that the need to reduce metabolic energy costs has slowed down mechanisms of lipid and fatty acid synthesis, lipid binding and transportation and adipocyte differentiation.
The downregulated contigs are involved in catabolic and biosynthetic metabolic process, transportation, and response to stimulus, showing protein binding, and catalytic activities within the cytoplasm, plastid, and mitochondrion cellular components (Additional file 9A).
Their typography and binding were exemplary.
And binding sniffers are not illiterate, anyway.
CTA decisions are final and binding".
Most contain plant material and binding agents.
The transportation and bioavailability of IGF-1 is facilitated by IGF binding proteins (IGFBPs) which circulate in the blood [ 5].
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