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Polar transport is a directional transport of functional molecules between cells, and plasma membrane transporters that localize in a polar manner are responsible for polar transport in most cases (Naramoto 2017).
+TIP function and activity range from influence on tubulin assembly to the transport of functional complexes toward cellular adhesion sites using polymerizing MTs as carriers.
Exosomes also contain and are capable of intercellular transport of functional mRNA and microRNA that can epigenetically reprogram recipient cells [17].
Like other cells that show chemotropic responses to BMPs, the onset of chemotaxis is too rapid to depend on classical Smad-mediated transcription, translation, maturation and transport of functional protein to the relevant cellular compartment.
Changes of polycystin-2 gene expression in the retinal cilia may lead to defective transport of functional proteins through this apparatus, although no change in the morphology of cilia in the TGR retina has been detected so far.
The skin penetration occurs through three possible routes: transcellular, intercellular, or follicular. 1, 2 The skin represents an important barrier to the penetration of exogenous substances into the body and also a potential route for the transport of functional active principles into the skin and hair.
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Translocation of miR395 led to a down-regulation of one of its targets in rootstocks, suggesting that this transport is of functional relevance, and that miR395, in addition to the well characterized miR399, could potentially act as a long-distance information transmitter.
The functions of the N-linked glycans attached to the IR include facilitating the correct folding of the protein, processing of the proreceptor and dimer formation, as well as the transport of the functional receptor to the membrane [4], [87], [88].
This aggregation of organelles and molecules has been observed in the developing oocytes of a large number of animals, and the selective transport of highly functional mitochondria to the Bb is thought to result in preferential transmission of a subset of mitochondria to the germ line [ 5– 7].
Although surgical procedures in the oral cavity, tongue, pharynx can affect preparation, control and transport of the bolus, functional disorders following laryngeal surgery are most common and severe.
The LeuT fold was subsequently observed in several other families of transporters, suggesting a possibly common mechanism of transport despite functional diversity.
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