Sentence examples for transport failure from inspiring English sources

These include: axonal transport failure, neurotrophic factor deprivation, toxic pro-neurotrophins, activation of intrinsic and extrinsic apoptotic signals, mitochondrial dysfunction, excitotoxic damage, oxidative stress, misbehaving reactive glia and loss of synaptic connectivity.

This transport failure leads to formation of axonal swellings, which are the physical manifestation of accumulation of axonal cargoes.

Interestingly, reduced microtubule acetylation and intracellular transport failure are regarded as early pathogenic events in the progression of Alzheimer's disease [10], [11].

However, since only certain neuronal populations appear vulnerable to ena down-regulation we favor the idea that specific cargoes are affected as opposed to a general transport failure, highlighting the exquisite regulation over motor proteins and their cargos.

Our data is consistent with the notion that reduced ENA levels impair the efficient flow of crucial cargoes to the synaptic terminals altering proper neuronal function, in turn leading to cell death (Figs. 5 7); a fast axonal anterograde transport failure, likely mediated by ENA-kinesin 1 interactions [40], could mediate this effect.

We next sought to identify the spatial distribution of axonal transport failure.

Their recent errors and accidents have reminded I.O.C. and Sydney officials of transport failures at the 1996 Atlanta Games.

Along with the DeLorean (which gained fame in the Back to the Future movies), Sir Clive Sinclair's C5 not only ranks as one of the most spectacular transport failures of 1980s, but it also has the dubious distinction of being named the worst gadget of all time – ahead of Betamax videos and pizza scissors.

Long distances to the health facilities, unavailability of public transport, and failure to meet transportation costs caused the labouring women to spend a long time on the road.

This paper presents a computational fluid dynamics model for simulation of two- dimensional (2-D) water flow, sediment transport, bank failure processes, and the subsequent channel pattern changes.

Progress towards a viable new resistive memory technology relies on fully understanding the mechanisms responsible for switching and charge transport, the failure mechanisms, and the factors associated with materials reliability.