Sentence examples for transport dysfunctions from inspiring English sources

A higher nerve length increases the vulnerability towards metabolic and transport dysfunctions [ 40].

This is important considering that many diseases of aging involve inaccurate microtubule organization coupled with transport dysfunctions.

The concept of phenotypic screens can be extended to include other toxicologically relevant end points by using additional fluorescent or other markers to probe other pathophysiological processes including steatosis, phospholipidosis, apoptosis, endoplasmic reticulum (ER) stress, protein trafficking and transport dysfunctions.

Functional studies of FHM support the hypothesis that ion transport dysfunction is one of the main factors determining susceptibility of the brain to migraine attacks.

Taken together these results are consistent with the notion that reduced ena levels causes transport dysfunction of certain specific cargoes thus contributing to the degenerative phenotypes.

Many studies have indicated that generation of free radicals, abnormal iron transport, dysfunction of mitochondria, gene mutations and drug-drug interactions are involved in ototoxicity induced by AGs [5], [6], [7], [8], [9], [10].

The locally produced ROS oxidize the cell membrane phospholipids and generate lipid hydroperoxides which impair membrane function such as membrane transport, dysfunction of channel proteins, and loss of fluidity leading to tissue injury [3].

We further employed CoQ10, a highly mobile electron carrier between the flavoproteins and cytochromes in the mitochondrial respiratory chain [21] and a potent antioxidant [22], to establish a causal relationship between mitochondrial electron transport dysfunction, bioenergetic failure and lack of resumed spontaneous circulation after cardiac arrest.

Together, these results suggest that glutamate transport dysfunction is a direct consequence of Htt171-82Q in astrocytes.

Weil, in advance of experimental evidence, first understood the origin of the sequence of events relating to oxygen transport dysfunction during circulatory failure [ 9, 10].

In contrast, Crish et al. [ 12] ascertained that axonal transport dysfunction and axon degeneration appear first at the superior colliculus with a distal-proximal progression, findings in broad agreement with earlier work [ 44].