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A fall in cellular oxygen use occurs in diverse disease states: oxygen uptake may be reduced (pulmonary disease), its mass transport diminished (cardiac contractile failure or anaemia), or its local delivery (microvascular disease) or cellular use (cellular dysoxia) impaired.
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Indeed, disrupting mitochondrial transport diminishes neuronal resistance to NMDA (N-methyl-D-aspartic acid -induced excitotoxicity [45].
In contrast, distal tubular cells are able to use glycolysis and endure severe hypoxic challenges better, provided that transport diminishes [ 69, 70].
In terms of operational parameters: feed fluid velocity is important in open loop configurations due to the effect upon ammonia residence time at the membrane surface; and, ammonia concentration did not notably impact the mass transfer coefficient which was ca. 1 × 10−5 m/s until in excess of 2000 mg/L wherein the transport process diminished.
(3) As was the case for the FG/FxFG gel, an excess of transport receptor diminished the passive influx into the gel.
It is possible that catalase may be critical in peroxidatically oxidizing ubiquinol or another periplasmic or inner membrane component using H2O2 as an electron acceptor during the stationary phase when the oxidizing capacity of the electron transport is diminished [ 21].
We previously showed that unesterified-cholesterol transfer to high-density lipoprotein (HDL), a crucial step in cholesterol esterification and role in reverse cholesterol transport, was diminished in non-diabetic patients with coronary artery disease (CAD).
Additional sites were measured to further investigate lateral transport, and diminishing concentrations of OA-d34 were observed up to 8 cm from the treatment site.
Metformin-mediated inhibition of the electron transport chain diminishes proton pumping, which might depolarize the mitochondrial membrane, thus limiting accumulation of the drug.
Interestingly, insulin-induced translocation of glucose through GLUT4 protein is dependent on microtubules, and without microtubules glucose transport is highly diminished [53] [55], suggesting that the decrease in expression of cytoskeletal genes in adipose tissue helps to spare glucose use by peripheral tissues.
Information was not collected on whether these symptoms persisted after December 2001, when fires were extinguished and dust from transport of debris diminished.
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CEO of Professional Science Editing for Scientists @ prosciediting.com