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Following microinjections into cultured cells, BC1 RNA fused to larger mRNAs appeared to impart transport competence to these chimeras, and its 5' ID region was proposed as the cis-acting dendritic targeting element.
To assess whether insertion of an ID element has the potential to impart dendritic localization, we generated transgenic mice with constructs that enabled us to test a somatic mRNA for potential acquisition of dendritic transport competence by inserting ID elements or the entire coding region of BC1 RNA into the 3' UTR of the reporter mRNA.
Among them, three encode DNA transport competence protein (ComeA), one encodes transposases and one encodes the TonB-dependent receptor.
The rationale for this assumption is the dimeric quaternary structure of wild type LPH that is generated in the ER and warrants enzymatic activity as well as transport competence of LPH [ 16].
Interestingly, wild type LPH retains its complete enzymatic activity and intracellular transport competence in the presence of the pathogenic mutants suggesting that heterozygote carriers presumably do not show symptoms related to CLD.
Similar(55)
The coarseness and flatness of the lensmBLA-facies lensoidal layers suggest a high capacity (ability to transport) and competence (erosiveness) of the flows, otherwise, the layers would build more steeply.
Interestingly, the comAB operon located downstream of the pcy genes also encodes an ABC transporter, which is known to process and transport the competence-stimulating peptide CSP (Fig. 3a) [ 39].
There are massive resources and competence to transport the whole industry".
Estimates of the reach-averaged critical shear stress are typically from competence, reference transport rate, or visual measurements.
(F, G, I, 65 89) if joking stories about the strategic use of an 'older' identity was one approach to depicting competent presentations of the self, another was the confident display of competence on public transport.
The history of driving simulators can be traced back to the 1920s when simulation was first used to evaluate the skill and competence of public transport operators [58].
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