Sentence examples for transport blocker from inspiring English sources

The objective of the study was to investigate changes in electrophysiological parameters after exposure to 0.01 M deltamethrin under unchanged conditions, in the presence of amiloride (sodium transport blocker) and bumetanide (chloride transport blocker).

This was suggested, since attenuation of the inhibitory effect of oxotremorine (10 μM) by McN-A-343 (3 μM) was suppressed by the A1 receptor antagonist, 1,3-dipropyl-8-cyclopentylxanthine (2.5 nM), and by reducing extracellular adenosine with adenosine deaminase (0.5 U/mL) or with the adenosine transport blocker, S- p-nitrobenzyl -6-thioinosine (NBTI, 10 μM).

However, stimulation-induced potentiation did also occur in the presence of the system A transport blocker MeAIB (5 mM, applied 5 min prior to stimulation; median 23.2±0.6 pA, n = 3; p>0.1 towards stimulated drug-free cells; Kolmogorov-Smirnov test).

We have established a subline (EMT6/VRP) of the mouse tumour cell line EMT6/P with acquired resistance to the calcium transport blocker verapamil (VRP).

We also showed that exogenous plant hormones cannot restore the inhibitory effects of NCS on root development (Additional file 1: Table S2), which is different from that of NPA, a general auxin polar transport blocker [ 58].

A deviation from the linear relationship, as observed with both 5-hydroxy l-tryptophan and α-methyl d, l-tryptophan, provides evidence for the inhibitory effects being due to the compounds acting as transport blockers rather than transported substrates.

Therefore to rule out the involvement of glutamate transport reversal in mediating hypoosmotic-stimulated excitatory amino acid release we used the broad-spectrum non-transportable glutamate transporter blocker DL-TBOA that blocks all neuronal and glial transporters [55], [54].

In PAT1, the levels of l-pipecolic acid translocation and competition are comparable, whereas in PAT2 it is a more effective blocker than transported substrate.

Cimetidine is also used as a blocker of cisplatin transport by OCT2 in zebrafish lateral line hair cells (Thomas et al., 2013) and the presence of OCT2-like proteins have been suggested in other teleost fish gill epithelia (Verri et al., 2012).

Conversely, Bania and colleagues [ 49] reported no adverse effect for oxfenicine, a blocker of fatty acid transport into mitochondria, on survival time during verapamil infusion in whole rats.

Key next steps involve determination of the sites and mechanism(s) of nephron ETA regulated Na transport, as well as how ETA blockers exert their fluid retaining effects.