Sentence examples for transport abnormalities in from inspiring English sources
The crypt defects observed in Rab8a knockout mice are likely to precede the apical transport abnormalities in enterocytes that are derived from the crypt progenitors.
For instance, in both SMA and ALS, defects in RNA metabolism are implicated, which mainly lead to splicing anomalies in the nucleus and mRNA transport abnormalities in the cytoplasm.
Furthermore, mitochondrial transport abnormalities are described in tg SOD1-ALS mouse models (De Vos et al., 2007).
Esophageal transport abnormalities can be investigated by esophageal impedance studies.
Therefore, inadequate endogenous LXA4 biosynthesis reported in CF exacerbates the ion transport abnormality and defective mucociliary clearance, in addition to impairing the resolution of inflammation, thus amplifying the vicious circle of airway dehydration, chronic infection, and inflammation.
In cystic fibrosis, ion-transport abnormalities cause problems in many organs.
The reduced dendritic branching and delayed maturation we observed might be due to deficits in the neuronal transport mechanism or abnormalities in cytoskeleton structures.
Blobel's work shed light on diseases such as cystic fibrosis, in which dysfunctional ion transporters give rise to abnormalities in cellular enzyme and protein transport.
On the other hand, as transthyretin is a thyroid hormone-binding protein that transports thyroxine from the bloodstream to the brain [20], the decreased level of transthyretin in CSF could imply abnormalities in thyroxine transport in brains of schizophrenia patients.
Amyloid, mutant huntingtin27,55, mutant TDP4318 and mutant FUS74 have all been associated with abnormalities in nucleocytoplasmic transport.
CF lung disease is regarded as a combination of abnormalities in electrolyte transport, epithelial lining fluid (ELF) composition, pathogen clearance and inflammatory response that set in motion a self-perpetuating cycle of airway obstruction, chronic bacterial infection and inflammation.
