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Some are involved in the activity of a second transmitter molecule, glutamate; others regulate the flow of calcium ions into cells.
As we can see from Figure 1, there are four components in a diffusion-based molecular communication system: transmitter, molecule, propagation medium, and receiver, whose functionalities are described as follows.
This has been demonstrated for monoamine or acetylcholine transport, which involve the exchange of one transmitter molecule for two vesicular protons (antiport) (Edwards, 2007).
Quantal sizes (Q in Coulomb) were derived from event integrals, and converted into the number of oxidized molecules by the equation [molecules = (Q × Avogadro's number)/n × Faraday constant), where n, the number of electrons transferred during oxidation of one transmitter molecule, is 4 for 5 HT [ 31, 38, 46].
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The transmitter molecules are then expelled from the vesicles into the synaptic cleft.
This critical input and output of communication (signaling) between neurons is mediated by chemical transmitter molecules (neurotransmitters).
Examples include RF radio communication in the terahertz band or molecular communication based on transmitter molecules.
Their electrical stimulation evokes the fusion of large dense core granules with the cell membrane and the exocytic release of multiple transmitter molecules into the circulation.
Third, granins may participate in the structural matrix of the granule lumen [20] and facilitate storage of transmitter molecules such as ATP and catecholamines [21], [22].
Cellular PTKs function as transmitter molecules in signaling pathways regulating important biological processes such as cell proliferation or cytoskeletal rearrangement [27], [41].
When an electrical impulse travelling through a nerve cell reaches one of these connections (called a synapse), it causes the cell to release chemical transmitter molecules.
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