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It is well known that for most infectious diseases, transmission intensity fluctuates through space and time1.
Gonçalves, B. P. et al. Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity.
Surprisingly, for example, we estimated high average COI in a peri-urban subregion with lower transmission intensity, suggesting that many of these cases were imported from surrounding regions with higher transmission intensity.
The most important result is that transmission intensity does not directly affect the evolution of resistance.
Measurements of anti-malarial antibodies are increasingly used as a proxy of transmission intensity.
Relationship between exposure, clinical malaria, and age in an area of changing transmission intensity.
However, longitudinal data do not indicate that reductions in transmission intensity lead to transient increases in morbidity and mortality.
We also predict the impact of IPT on transmission intensity.
In contrast to our previous study done in an area of high transmission intensity, this trial was conducted in an area of moderate transmission intensity in Uganda.
There is evidence that the age-pattern of Plasmodium falciparum malaria varies with transmission intensity.
The increased impedance mismatch that re-occurs will also decrease the transmission intensity.
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