Control of TB is complicated by its ease of transmission, difficulty in administering the long-course chemotherapy regimens, and subsequent appearance of multidrug-resistant strains (MDR-TB).
They also display several other disadvantages: risk of disease transmission or infection, difficulties in obtaining and processing, possible rapid resorption, [ 8– 10, 24], and partial loss of mechanical strength after sterilization [ 25, 26].
Contrary to reports by other authors from different European countries [ 18], human CE case numbers are underestimated [ 17] due to the peculiarities of CE transmission and difficulty in reading clinical presentation [ 19].
Mr. Pickens had once planned to build his own transmission lines, but difficulty in finding financing amid the credit crisis forced him to shelve that plan.
Broadband transmissions pose new difficulties but also permit the implementation of more complex IA schemes.
At first it seemed to me that the engine and transmission had some difficulty agreeing on what gear they liked, especially during hard acceleration.
Even a slight frequency or phase difference between the image sampling processes of the cameras would lead to difficulties during transmission and post processing.
Very severe cases, such as hemorrhagic or flat smallpox, occasionally resulted in considerable transmission, owing to diagnostic difficulties; mild cases, in which the patient remained ambulant during the course of the disease, could cause considerable spread as well [ 35, 36].
It remains unclear whether differences in reproduction number estimates across locations and pandemic waves reflect true differences attributable to variation in attack rates or local factors affecting transmission or merely illustrate difficulties in measuring this parameter with precision (38 ).
