Sentence examples for translocation there from inspiring English sources

50 At the time of the translocation there were three genes within the region.

Because primer strand transfer from the polymerase site to the exonuclease site precedes translocation, there is a kinetic competition between primer transfer and the forward translocation.

While a great deal is known about the effects of the Philadelphia translocation, there is limited knowledge of the recombinational mechanisms that lead to genomic rearrangement.

For each translocation, there was a probability Kon to transition from D1 to D2, and a probability Koff to transition from D2 to D1.

Load induced partial β-catenin nuclear translocation; there was an additive effect of load and Wnt3A on β-catenin distribution, with both extensive localisation in the nucleus and cytoplasm.

In cells without the translocation, there was enrichment of heterochromatic features such as EZH2 and H3K27me3 for those genes that become silenced when translocated, suggesting that underlying chromatin structure predisposes genes towards silencing.

In contrast to the increase of chromosome translocations, there was no increase in chromosome deletions, although there was a nickel dose-dependent reduction of mitotic indices.

Since these two lines carry different BRD4 NUT translocations, there may be important differences in BRD4 and/or CDK9 signalling that relate to both growth pattern and FP sensitivity in an in vivo context.

For carriers of balanced structural chromosome rearrangements, particularly reciprocal or Robertsonian translocations, there is a high risk of segregating unbalanced combinations of the normal and derivative chromosomes in meiosis, which can result in infertility, repeated miscarriage, or affected live births depending on the chromosomes involved and the size of the translocated segments.

In subsequent ISWI binding, there is no "memory" of the previous direction of translocation, so there is equal probability of the octamer moving in either direction.

Notably, different levels of sensitivity seen in six other mutant variants A231G, V364A, M132A, P512A, S505A and V496A points to the fact that even though there is a single pore for proton antiport and drug binding and translocation, yet there are residues which impart selectivity in drug recognition along with those which affect the transport of all the drugs.