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Previous studies that involved translocation of embryos from Meishan to Large White sows indicated that the number of conceptuses transferred at gestation day 30 is generally reduced during late gestation as a result of the limited ability of the uterus to maintain a large number of fetuses to term [ 13].
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The aim of this study was to summarize our experience using preimplantation genetic diagnosis after the identification of a parental balanced translocation, specifically as it relates to the number of embryos that are suitable for transfer after preimplantation genetic diagnosis for a known translocation and aneuploidy screening.
The depleted embryos are deficient for translocation of germ plasm from the cortex to the perinuclear region in PGCs before midblastula transition (MBT), causing inhibited PGC division.
We also found that aberrant translocation of germ plasm occurred in DEADSouth-knockdown embryos at stage 12, but not at stage 7 (Fig. 5B).
Because LIN28 is deposited in the nucleoplasm of zygotes and early 2-cell embryos, we envision a translocation of the maternal protein from the nucleoplasm to the periphery of active NPBs at the late 2-cell stage.
N is the number of embryos examined.
In Germany last week, the parliament approved genetic testing of embryos.
(number of embryos harboring mutations/total number of examined embryos).
Thus, the emergence of sensory neuron-like cells in the spinal cord of Six1/4 EGFP/EGFP embryos could be due to translocation of NCCs into the spinal cord, and the most probable mechanism for such translocation is a change in the intrinsic properties of NCCs.
One explanation for this discrepancy is that a genomic rearrangement or translocation of part of the concatemer occurred in the developing embryo after injection of SB11 transposase mRNA.
This finding offers an explanation for why inhibition of Egl and BicD following translocation of localising RNAs to the apical cytoplasm of the embryo does not affect dynein-dependent anchorage (Delanoue and Davis, 2005).
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