Sentence examples for translocation blockade from inspiring English sources

These examples highlight the important point that translocation blockade effectively 'trumps' any effect of pre-translocation events.

This is especially true if you consider translocation blockade because of the large range of potentially affected proteins.

Mycolactone exposure also has effects on the cytosolic component of T-cells that are not confounded by translocation blockade.

We also found the protein level of membrane Hsp90α was consistent with the inhibition of PKCγ activation induced by its translocation blockade.

This interaction, along with the binding of the antibiotic to the 23S rRNA in the large subunit, also causes translocation blockade and inhibition of ribosome recycling.

With hindsight, it now seems likely that the expression defects for these ER-transiting proteins may be mediated by translocation blockade.

The prevention of STAT3 nuclear translocation, the blockade of the binding of activated STAT3 to its consensus DNA sequence, and the suppression of STAT3-directed transcriptional activity confirmed silibinin as a direct STAT3i.

At advanced stages of disc translocation and blockade, acoustic symptoms disappear to be replaced by chronic pain and significant restriction of jaw opening range, complicated by tilting the mandible towards the affected side upon abduction.

Impaired TGFβ1-dependent Smad2/3 nuclear translocation with KCa3.1 blockade predicts that TGFβ1-dependent gene transcription will also be inhibited.

Both translocation time and current blockade were measured to investigate the translocation behaviors.

Atomic detail of the associated mechanism reveals that, rather than a collapse of the pore, as proposed for other K2P channels gated at the selectivity filter, an increased height of the energetic barriers for ion translocation accounts for channel blockade at acid pHo.