We show here that the ability of G protein γ subunit types to translocate away from the plasma membrane on receptor activation controls sensitivity of response.
From these sites, cohesin appears to translocate away towards sites of convergent transcriptional termination (Ciosk et al, 2000; Lengronne et al, 2004).
DOI: http://dx.doi.org/10.7554/eLife.08722.003 Shortly after their generation, proliferating intermediate precursors translocate away from the proximal domain and into the intermediate domain (Fuentealba et al., 2012).
This is consistent with the idea that cohesin loads onto defined chromosomal sites, such as centromeres, and then subsequently translocates away from these sites into the adjacent part of the chromosome [ 10, 20].
With pro-inflammatory stimuli, ZO-1, occludin and claudin-5 expression levels are decreased [ 11, 12], whereas JAM-A translocates away from tight junctions, without any expression changes [ 13].
Subsequently, cohesin translocates away from its loading sites to generate the pattern observed at metaphase (Lengronne et al. 2004).
Neural crest cells become migratory and translocate away from the forming neural tube to various locations within the embryo, where they give rise to a wide array of cell types and tissues, including the Schwann cells of the peripheral nervous system (Le Douarin and Kalcheim, 1999).
There has been some attempt by CALM to translocate populations away from hazardous areas; these have met with some success, helped with watering in the first year.
The fenestrated and branched EVAR techniques have gained popularity as a possible alternative to open repair or standard EVAR techniques that would not compromise blood perfusion to the aortic side branches, since the sealing and/or fixation zone is translocated proximal or distal away from the target vessels [ 4, 5].
