Sentence examples for translational tool from inspiring English sources

More recently, these methods have been extended to preclinical species, thus providing a powerful translational tool.

For a constant rotational speed, softening of the weld nugget reduces as the feed rate or translational tool velocity is increased (Krishnan 2002).

In order for [18F]FDG-6-P to be a potential translational tool for the specific diagnosis of bacterial infections, it should not be transported into mammalian cells.

The ability to directly radiolabel nanotherapeutics offers a valuable translational tool to obtain biodistribution and tumor deposition data, testing the hypothesis that the extent of delivery predicts therapeutic outcome.

These results strongly resemble the clinical observations obtained with MEK/Raf inhibitors support the use of preclinical [18 F]FDG-PET as a translational tool for decision support in preclinical and early clinical development of MEK inhibitors.

The ability to directly and stably radiolabel nanotherapeutics such as MM-302 offers the possibility of adapting these molecules for combined therapy and diagnostic imaging and provides a valuable translational tool to obtain quantitative biodistribution and deposition data for therapeutic agents.

Novel molecular and translational tools will provide further opportunities to define host parasite interactions and design effective transmission-blocking therapeutics.

This gap illustrates the need for carefully designed in-depth studies using valid models and translational tools which allow to uncover the observed events up to the molecular level.

Based on this consideration, several studies reported in the last few years were designed to validate sensitive and reliable translational tools to mechanistically characterize brain bioavailable polyphenols as disease-modifying agents to help prevent the onset of AD dementia and other neurodegenerative disorders.

Over the past 10 years, strategies for mouse behavioral phenotyping have evolved to maximize the scope and replicability of findings from a cohort of mutant mice, minimize the interpretation of procedural artifacts, and provide robust translational tools to test hypotheses and develop treatments.

These translational tools could also facilitate the development of personalized medicines.