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Thus, Foxo targets impose a translational program by activation of genes that repress general translation while simultaneously activating targets that are immune to this translational control.
This work has been recognized by a translational program grant from Boston Children's Hospital, by NSF, NIH, and Autism Speaks.
Taken together, our data shows that ATM kinase activation during the DNA damage response modulates Tia1 dissociation from its mRNA targets and controls a translational program to produce key proteins that induce cell cycle arrest and promote DNA damage repair and apoptosis.
Barbara Jones, who's enrolled in a clinical and translational program at the University of Massachusetts Medical School, completed a project on adipose-derived stem cells in the Tissue Engineering and Wound Healing laboratory of her mentors Giorgio Giatsidis and Dennis Orgill at Brigham and Women's Hospital.
The professorship was established to build a basic science and translational program in food allergy research at the University.
We should have a general idea of the current situation, developing trend and new collaboration models of translational medicine thus we can find a right way to promote translational program.
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The appointment of Dr. Alpern in 2004 has strengthened the commitment of the University to medical research, as evidenced by the decision to support the development of translational programs, and YCCI in particular.
The project team must include a Project Manager who has experience in managing relevant translational programs and who is able to devote at least 35percentt effort to the project.
The overriding objective of the CTSA is to integrate and enhance current clinical and translational programs and resources within an institution to produce a new home for clinical and translational research that is far greater than the sum of its individual parts.
We conclude that Tor signals via Sap-Sit4 complexes to control both transcriptional and translational programs that couple cell growth to amino acid availability.
The new center also stirred a firestorm of debate among NIH-supported researchers because it entailed breaking up an existing center at NIH. Austin, 52, is a developmental neurogeneticist who spent 7 years at Merck before joining NIH to oversee translational programs at NIH's genome institute.
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